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Quan-Plex™ Patient-like ctDNA Panel


Description:

 The Quan-Plex™ ctDNA Reference Standard is a highly-characterized, quantitative multiplex quality control that allows researchers to develop their own assays, and assess limits of detection (LODs) for eight cancer-associated solid tumor mutations.  This panel can also be used to monitor the quality of their NGS or dPCR oncology-based workflow for routine quality assessment.  The standards have been engineered to mimic the fragmentation profile of nucleosomal, ctDNA in patient (~166 bp) samples.

Price: $450.00

Datasheet MSDS

Certificate of Analysis
291725 ARF1003CT291725

Variant Information:
Gene Nucleotide Amino Acid Cosmic Frequency
EGFR 2307_2308insGCCAGCGTG V769_D770insASV COSM12376 0%, 0.1%, 1%, 5%
EGFR 2573T>G L858R COSM6224 0%, 0.1%, 1%, 5%
EGFR c.2369C>T p.T790M COSM6240 0%, 0.1%, 1%, 5%
KRAS 35G>A G12D COSM521 0%, 0.1%, 1%, 5%
NRAS c.181C>A p.Q61K COSM580 0%, 0.1%, 1%, 5%
PIK3CA c.1633G>A p.E545K COSM763 0%, 0.1%, 1%, 5%
EGFR 2235_2249del15 E746_A750delELREA COSM6223 0%, 0.1%, 1%, 5%
EGFR 2155G>A G719S COSM6252 0%, 0.1%, 1%, 5%
General Information:
CatalogARF-1003CT
Size1 panel
FormatctDNA
Volume/Dimension4 vials of 7.5µl each
Quantity300 ng/vial
Concentration40 ng/µl
Cell(s)RKO, HCT116
Shelf Life24 months
BufferTris-EDTA (10 mM Tris-HCl, 1 mM EDTA), pH 8.0
Shipping TemperatureGel packs
Storage Temperature-20°C (2 years Exp Date)
Quality ControlGenotype: Sanger sequencing of locus-specific PCR (cell line)
Quality:Bio-Analyzer™ 1000 Chip and NGS (Ion AmpliSeq Hotspot Cancer Panel V2 on Illumina) DNA Quantification: Qubit 4.0 fluorometer
Mutation Allelic Frequency: Digital PCR **Quantified with NGS. Note multiple copies of the insertion may be observed with NGS. Manufacturing: ISO 9001:2015 and ISO 13485:2016 Certified
Freeze/ThawNo more than 3 cycles
RegulatoryFor Research Use Only. Not intended for human or animal diagnostics or therapeutics.
RestrictionsThis is a limited use product. This product, any material that contains this product in whole or in part, any progeny, modification or derivative of this product, any cell or animal made or modified by using this product, and any progeny, modification or derivative of such cell or animal may not be transferred by the purchaser to any other person, entity or any of the above to perform services for the benefit of any other person or entity or for commercial purpose of any kind. This product may only be used by the purchaser for its internal research for use as a research tool for research purposes.
Catalog: ARF-1003CT
Price: $450.00
Availability: In Stock
© 2018 Copyright AccuRef Diagnostics, a Division of Applied StemCell Inc.
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